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Real members of MyBCTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyBCTeam Member asked a question 💭
Lansdowne, PA

Every day I read so many posts from women who had lumpectomies or mastectomy, did chemo and radiation but then say they are too afraid of taking a hormone blocker drug. I get it. I have refused the drugs they use for stage 4 Breast cancer because of the possible harsh side effects and the lack of quality of life I would have. But I am more concerned about women who have early stage cancers and go through all the other treatments but won't take an AI to protect themselves from any stray cells… read more

January 30, 2025
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Answer Summary

Members overwhelmingly agreed that aromatase inhibitors, while difficult, offer critical protection against early-stage breast cancer... Read more

Members overwhelmingly agreed that aromatase inhibitors, while difficult, offer critical protection against early-stage breast cancer recurrence, with many emphasizing that dormant cancer cells can remain in the body for years and that side effects reverse once treatment ends. Several members shared strategies for managing side effects, including switching between anastrozole, letrozole, and exemestane to find the most tolerable option, taking high-dose vitamin D3 (5,000-7,000 IU daily) to protect bone health, trying Claritin for joint pain, exercising regularly despite discomfort, and considering palliative radiation for bone metastases if recurrence occurs. A recurring theme was the deeply personal nature of the decision, balancing quality versus quantity of life, with members acknowledging that factors like age, cancer stage, caregiving responsibilities, and individual tolerance levels all play a role, while offering fierce encouragement to at least try the medications and not let fear prevent protection after already enduring surgery, chemotherapy, and radiation.

A MyBCTeam Member

I was iffy about it because I feared osteoporosis. My GP had the same kind of cancer I had and she said that exercise (strengthening) can prevent that and even reverse osteoporosis. I got a baseline bone scan. When I get another a year later they can see how my bones are doing. I don't have hot flashes or any other side effects. My oncologist said that my chances of recurrence are about 9 percent without the anastrozole and about 3 percent with it. A friend with a similar cancer told me that women who take it live on average 4 years longer. BTW I didn't know about stray cancer cells hanging around that cause recurrence. That makes sense. Thanks for that info. I hope everyone will do what's best for her. Quality of life has to be considered. I'm going to continue with the Anastrozole. I've saved every bottle (including the instructions that are glued to every bottle cap). I'm going to make a sculpture with the 60 bottles. Goodnight 😴❤️.

January 30, 2025
A MyBCTeam Member

Respectfully, AIs reduce the risk - not eliminate the possibility - of recurrence. I don't tell anyone else what to do but I'm comfortable with the decisions I've made. ☺️

January 30, 2025
A MyBCTeam Member

I am on the five year exemestane treatment. I’m on year 2 and I’m 78. I have faith in my oncologist, and that’s what she thought was best for me. If I get to a point where I think it’s affecting me negatively, I will stop it, but taking it gives me hope that it won’t come back.

February 9, 2025 (edited)
A MyBCTeam Member

Thank you for your post Barbara. I finished up radiation in May and I had already refused chemo. I was stage one grade 2, and based on the mamma, print test had a higher risk of recurrence . I have yet to take the AI because I was too afraid of the side effects. I think now I should at least try it.

January 31, 2025
A MyBCTeam Member

One of the worst side effects of AIs is that they cause osteoporosis, or make it worse if you already have it. Yes, there are drugs that can help lessen this side effect of AIs, but they have their own scary side effects. When the drug you're taking to lessen the side effect from one drug has its own set of side effects, it's time to consider whether to go down the rabbit hole of promises or opt for quality of life.

January 30, 2025

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Newberg, OR

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