Onc took me off after my 1st week (off for a week) because my D was so bad and I was vomiting too. After I restarted Nerlynx, it's been more manageable.

No, never too Chollestyramine. I'm so sick of taking so many pills with all the side effect meds.

Yes. I've only been on the Nerlynx less than 3 months. I took the budesonide w/the nerlynx for about a month and a half. Onc did not want me to stay on budesonide. When did you start? FYI- there is a great Facebook Nerlynx support group. You should join if you are not already on it. Here is the official name: Nerlynx (Neratinib) Support Group

Scrap, how is your GI system doing now?

I started March 14th. Why did onc want to take you off?
Yesterday I had a normal BM with no diarrhea! Have you ever taken that cholesterol medication to help control diarrhea? I think it is called Cholestyramine.