I started welchol 625mg and it completely stopped the diarrhea! Its used to lower cholesterol and lower blood sugar but the off label use is as a bile binder. My diarrhea was fluorescent yellow and that indicates bile from your liver (prob freaking out from the chemo) and the welchol stopped it cold. Hallelujah!

I take one every 6 to 8 hours for a week after each Herceptin treatment. If I feel constipated, I stop taking until I have another bout of diarrhea.

how did you take it? before eating, or after loose stools, or 2 4x a day spaced evenly?
I've heard all 3. my doc told me to take it after loose stools & it doesnt seem to help. only tried it twice...

I got put on Lomotil which cut my diarrhea back from 6 bouts a day to 2 or 3. Yes I was fairly housebound for a couple months, but I didn't need to worry about having uncontrolled leaks.

i am doing the opposite - switching from taxotere (docetaxol) to taxol. I am switching because of the debilitating gastrointestinal effects. Severe abdominal cramping and diarrhea that made me housebound. I even had accidents soiling myself while sleeping at night. horrifying!